During the Second World War the Regiment mobilized the 18th (Manitoba) Reconnaissance Battalion, CAC, CASF, for active service on 10 May 1941. It was redesignated the 18th (Manitoba) Armoured Car Regiment, CAC, CASF, on 26 January 1942; the 18th Armoured Car Regiment (12th Manitoba Dragoons), CAC, CASF, on 16 December 1942; and 18th Armoured Car Regiment (12th Manitoba Dragoons), RCAC, CASF on 2 August 1945. It embarked for the Great Britain on 19 August 1942. On 8 and 9 July 1944 it landed in Normandy, France as a unit attached directly to II Canadian Corps, where it fought in North-West Europe until the end of the war.