On February 10, 1940, the colonel-in-chief, Princess Patricia, inspected her regiment for the first time in twenty-one years. The regiment spent three and a half years in United Kingdom, most of which was spent in coastal defence and training in various parts of the country
On July 10, 1943, the PPCLI, forming part of the 1st Canadian Infantry Division and the British Eighth Army, landed in Sicily during Operation Husky. The Patricia won its first battle honours of the Second World War at Leonforte. Later, on September 4, 1943, the regiment landed and fought in Italy, advancing North for two months